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Pristiq 50 mg Extended Release Tablets 30 Pieces Eye Care they may go away withinProduct Description. Pristiq is a brand name prescription drug thats used to treat major depressive disorder (MDD) in adults. MDD is a serious mental health condition. Its often called clinical depression, or simply depression. Dosage. The Pristiq dosage your doctor prescribes may depend on a few factors, including how well your liver and kidneys work. Side Effects. nausea dry mouth fatigue (lack of energy) dizziness sweating constipation reduced